The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
20045645 |
66 |
Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist. |
Roche Palo Alto |
12213051 |
207 |
Purine and pyrimidine (P2) receptors as drug targets. |
National Institute of Diabetes |
19231180 |
81 |
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain. |
Roche Palo Alto |
19231178 |
61 |
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain. |
Roche Palo Alto |
26460788 |
45 |
Novel Series of Dihydropyridinone P2X7 Receptor Antagonists. |
Hoffmann-La Roche |